Eosinophilic myositis/perimyositis: frequency and spectrum of cutaneous manifestations.

نویسندگان

  • R M Trüeb
  • M Pericin
  • B Winzeler
  • B Wüthrich
  • G Burg
چکیده

BACKGROUND Eosinophilic myositis/perimyositis (EM/P) are a group of rare idiopathic muscle disorders associated with eosinophilia. OBJECTIVE We describe the frequency and spectrum of cutaneous manifestations in EM/P and compare them with the idiopathic hypereosinophilic syndrome (HES). METHODS We review the literature on EM/P and describe an additional case associated with angioedema. RESULTS Of a total of 26 reported patients with EM/P, cutaneous manifestations were observed in 10. These were, in order of frequency, deep subcutaneous induration, erythema, angioedema, urticaria, and papular lesions. CONCLUSION Skin lesions occur less frequently in EM/P than in HES. Although erythematous papulonodular lesions and urticaria/angioedema are most commonly observed in HES, the most frequent skin manifestations of EM/P are subcutaneous induration and erythema. In HES, angioedema has been correlated with a favorable prognosis. At least some of these patients apparently have an idiopathic eosinophilic disorder distinct from HES, including EM/P. In contrast to HES, the overall prognosis of EM/P is good, particularly when muscle lesions are focal, and the principal histopathologic finding is perimysial infiltrates.

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عنوان ژورنال:
  • Journal of the American Academy of Dermatology

دوره 37 3 Pt 1  شماره 

صفحات  -

تاریخ انتشار 1997